Motif ID: TLX1..3_NFIC{dimer}.p2

Z-value: 2.812


Transcription factors associated with TLX1..3_NFIC{dimer}.p2:

Gene SymbolEntrez IDGene Name
TLX1 3195 T-cell leukemia homeobox 1
TLX3 30012 T-cell leukemia homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TLX3chr5_+_170668892-0.476.3e-02Click!
TLX1chr10_+_102881050-0.457.8e-02Click!


Activity profile for motif TLX1..3_NFIC{dimer}.p2.

activity profile for motif TLX1..3_NFIC{dimer}.p2


Sorted Z-values histogram for motif TLX1..3_NFIC{dimer}.p2

Sorted Z-values for motif TLX1..3_NFIC{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX1..3_NFIC{dimer}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_102340579 11.319 NM_001031692
NM_005824
 LRRC17

leucine rich repeat containing 17

chr7_+_115952279 8.940 NM_001172895
 CAV1
caveolin 1, caveolae protein, 22kDa
chr7_+_115952325 8.499 CAV1
caveolin 1, caveolae protein, 22kDa
chr7_+_115952074 8.471 NM_001753
 CAV1
caveolin 1, caveolae protein, 22kDa
chr12_+_13240868 7.367 NM_001423
 EMP1
epithelial membrane protein 1
chr12_+_13240987 6.807 EMP1
epithelial membrane protein 1
chr1_-_171441234 6.192 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr14_+_85066207 6.142 NM_013231
 FLRT2
fibronectin leucine rich transmembrane protein 2
chr12_-_54392328 6.102 NM_001144997
 ITGA7
integrin, alpha 7
chr21_+_45699830 6.027 NM_030582
NM_130444
 COL18A1

collagen, type XVIII, alpha 1

chr2_-_218551786 5.783 TNS1
tensin 1
chr8_-_42184194 5.733 PLAT
plasminogen activator, tissue
chr8_-_42184350 5.583 NM_000930
NM_033011
 PLAT

plasminogen activator, tissue

chr15_-_32875040 5.575 NM_005159
 ACTC1
actin, alpha, cardiac muscle 1
chr16_+_69060325 5.482 FUK
fucokinase
chr17_-_74433048 5.336 NM_003255
 TIMP2
TIMP metallopeptidase inhibitor 2
chrX_+_99785818 5.247 NM_014467
 SRPX2
sushi-repeat containing protein, X-linked 2
chr17_-_74432800 4.966 TIMP2
TIMP metallopeptidase inhibitor 2
chr17_-_74432671 4.800 TIMP2
TIMP metallopeptidase inhibitor 2
chr12_+_64504408 4.714 NM_003483
NM_003484
 HMGA2

high mobility group AT-hook 2


Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
2.02 4.56e-02 GO:0009986 cell surface
1.68 4.59e-03 GO:0044421 extracellular region part
1.67 4.17e-02 GO:0005615 extracellular space
1.45 2.61e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
5.93 4.78e-02 GO:0008060 ARF GTPase activator activity
2.38 4.27e-02 GO:0046982 protein heterodimerization activity